Certified Diabetes Educator Practice Exam

Marfan syndrome is primarily characterized by effects on the connective tissue, leading to symptoms such as tall stature, long limbs, and a range of cardiovascular problems. Although individuals with Marfan syndrome may experience other health issues, the direct relationship between this syndrome and diabetes is not well established.

In contrast, Klinefelter syndrome, Down syndrome, and Turner syndrome have established links to an increased risk of developing diabetes. Klinefelter syndrome can lead to metabolic issues and obesity, which raise diabetes risk. Individuals with Down syndrome often face challenges such as obesity and decreased physical activity that can contribute to diabetes. Turner syndrome, characterized by the absence of part or all of a second sex chromosome, is associated with insulin resistance and a higher prevalence of type 2 diabetes.

Therefore, Marfan syndrome stands out in this context as it does not have a recognized association with the onset of diabetes, making it the correct choice in this question.