Certified Diabetes Educator Practice Exam

Question: 1 / 400

What side effect is most likely to occur with Glyburide use?

Weight loss

Hypoglycemia

Glyburide is a sulfonylurea used in the management of type 2 diabetes, and its primary mechanism of action involves stimulating the pancreas to produce more insulin. This increased insulin production can lead to a greater risk of blood sugar levels falling too low, which is known as hypoglycemia. This side effect is particularly significant for patients taking glyburide due to its potent insulin secretory effect and the timing of food intake in relation to medication administration.

When managing diabetes with medications that stimulate insulin release, healthcare providers must be vigilant about monitoring glucose levels to prevent hypoglycemic episodes, especially when initiating therapy or adjusting dosages. Patients are typically educated about recognizing the signs and symptoms of hypoglycemia, such as sweating, trembling, confusion, and dizziness, to ensure prompt treatment.

The other options present symptoms or effects that are less commonly associated with glyburide. Weight loss is more often linked with other diabetes medications, such as GLP-1 receptor agonists. Injection site reactions are typically associated with injectable medications, while gastrointestinal discomfort can result from various medications but is not as specific or prevalent with glyburide compared to the risk of hypoglycemia.

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Injection site reaction

Gastrointestinal discomfort

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